Manipulating dna repair for improved genetic engineering in aspergillus christina spuur nødvig phd thesis technical university of denmark department of systems biology. Item type: phd thesis title: dna repair and chromatin language: english abstract: laser microirradiation can be used to induce dna damage with high spatial and temporal resolution, representing a powerful tool to analyze dna repair in living cells however, most lasers induce a mixture of dna. Characterisation of the role of autophagy in dna damage repair liu, emma yu ( 2014) characterisation of the role of autophagy in dna damage repair phd thesis, university of glasgow full text available as:. Characterisation of xpd from sulfolobus acidocaldarius: an iron-sulphur cluster containing dna repair helicase jana rudolf a thesis submitted for the degree of doctor of philosophy october 2006 university of st andrews. Although some hmgb proteins including hmgb 1 inhibit the repair of platinated damage on dna in vitro, experiments conducted in live cells reveal conflicting correlation thesis (ph d in inorganic chemistry)--massachusetts institute of technology, dept of chemistry, 2012 cataloged from pdf version of thesis vita.
Dna repair defects in prostate cancer cells in response to radiation a dissertation submitted to kent state university in partial fulfillment of the requirements for the degree of doctor of philosophy by payel chatterjee august 2014. Failure to replicate dna correctly leads to mutations these mutations can cause progenitor cells to have defects and die, or can cause cancer in higher organisms dna mismatch repair (mmr), the subject of study in this thesis, increases the fidelity of replication by removing mismatches left by the. Sachin katyal, phd modulating dna damage repair mechanisms to enhance brain tumour treatment success dna strand breaks occur on a daily basis in cells due to cell stress 1st place, three-minute thesis (3mt) competition, cancercare manitoba, research institute in oncology and hematology annual retreat. Base excision repair (ber) is the primary pathway for repair of oxidative dna damage caused by various agents including reactive oxygen species ber is initiated by dna glycosylases that recognize and remove damaged dna bases, and the function of the glycosylases ogg1, mutyh, neil1, and neil2 are the main.
Abstract casein kinase 2 (ck2) is a ubiquitous serine/threonine kinase due to its pleiotropic nature ck2 is involved in a multitude of cellular pathways including cell survival, proliferation and apoptosis therefore it has come as no surprise that a requirement for ck2 activity has been identified during the repair of dna. Thesis for the degree of doctor of philosophy (phd) uv- irradiation induced dna-damage and repair in skin cells in vitro methods gabriella emri md supervisors: prof irén horkay md phd, remenyik éva md phd university of debrecen medical- and health science.
Stalled replication forks upon dna damage doctoral thesis (phd dissertation) andreea daraba supervisor: dr ildikó unk doctoral school of biology of the 15 ubiquitin and its role in proteasomal degradation and dna damage bypass 29 35 generation of deletion strains by homology based gene replacement. Computational analysis of dna repair pathways in breast cancer chao liu bachelor's and phd in microbiology a thesis submitted for the degree of doctor of philosophy at the university of queensland in 2016 institute for molecular bioscience. Computational analysis of dna repair pathways in breast cancer liu, chao ( 2016) computational analysis of dna repair pathways in breast cancer phd thesis, institute for molecular bioscience, the university of queensland doi: 1014264/uql2016278.
Dna repair and genomic stability in aging phd thesis by guido keijzers, department of cellular and molecular medicine, faculty of health and medical sciences, university of copenhagen the minor binding pocket - an important region for 7tm receptor activation phd thesis by anne marie førrisdahl steen, department. Monica dahl bjørge defended her phd thesis on impact of oxidative dna damage repair on brain function 6 march 2017 monica dahl bjørge defended her phd thesis on impact of oxidative dna damage repair on brain function supervisers: magnar bjørås and gunn annette hildrestrand - department of microbiology. These proteins are highly conserved from bacteria to humans and have been implicated in functions from homologous recombinatorial repair to damage checkpoint response loss of helical structure at this site leads to increased genomic instability and sensitivity to dna damaging agents doctor of philosophy (phd).